9:30am Key Success Factors for Bispecific ADCs; Target & Format Selection
Time: 9:30 am
day: Bispecific ADC Seminar Day
Details:
- Lessons from past ADC development, including: The importance of PK above TMDD (targetmediated drug deposition), payload with safety margin, and understanding of off-target toxicity
- Bi-specific target selection criteria: mechanistic synergy vs. target patient coverage
- Bi-specific format selection criteria: 2+2 vs. 1+1
