2:30pm Evaluating Efficacy & Safety of Dual-Payload ADCs in Preclinical Models to Establish Their Value Over SinglePayload Alternatives
Time: 2:30 pm
day: Day One Preclinical & Clinical Development Track
Details:
- Discussing the unique challenges of demonstrating efficacy for dual-payload ADCs compared to single-payload ADCs, which often achieve complete regression in preclinical studies
- Exploring experimental designs to assess the added therapeutic potential of dual-payload ADCs in tumor models
- Identifying the approach to accurately predicting ADME properties of dual-payload ADCs
