11:00am Assessing Lysine vs. Cysteine Conjugation Method for Achieving Enhanced Homogeneity of the Drug Substance in ADCs
Time: 11:00 am
day: Day One CMC Track
Details:
- Comparing the individual challenges of lysine and cysteine stochastic conjugation and how it affects attributes of the ADC
- Site-specific vs. stochastic conjugation strategies to achieve controlled drug-to-antibody ratios (DAR)
- Examining the distinct process development requirements for each conjugation approach to ensure optimal outcomes
