Pooja Desai

Company: Exelixis

Job title: Biotherapeutics CMC Director

Seminars:

11:00am Assessing Lysine vs. Cysteine Conjugation Method for Achieving Enhanced Homogeneity of the Drug Substance in ADCs 11:00 am

Comparing the individual challenges of lysine and cysteine stochastic conjugation and how it affects attributes of the ADC Site-specific vs. stochastic conjugation strategies to achieve controlled drug-to-antibody ratios (DAR) Examining the distinct process development requirements for each conjugation approach to ensure optimal outcomesRead more

day: Day One CMC Track

11:30am Roundtable Discussion: Navigating the Timeline Pressure on Manufacturing in an Increasingly Competitive ADC Landscape 11:30 am

Assessing rate-limiting hurdles in ADC process development and manufacturing to keep up with accelerated submission timelines Debating the use of real-time experimental data to take on calculated risk and undergo parallel development Optimizing end to end internal alignment to ensure ADC supply chain efficiencyRead more

day: Day One CMC Track