Effective PK/PD Translational Strategies to Enable a Successful Early Clinical Development
Time: 5:00 pm
day: Day Two
Details:
- Defining the translational PK/PD considerations for ADC FIH starting dose prediction
- Integrating nonclinical knowledge through computational modeling and simulations to inform Phase I design dose escalations.
- Exploring translational PK/PD data to support model-informed clinical safety mitigation strategy, drug-drug interaction risks
