12:00pm Drug Linker Properties Impacting Hydrophobic Interaction Chromatography for Determining DAR
Time: 12:00 pm
day: Day Two CMC Track
Details:
- Outlining how the drug-to-antibody ratio (DAR), which is one of the critical quality attributes (CQAs) for ADCs, is evaluated.
- Exploring which ADC properties impact hydrophobic interaction chromatography (HIC)
- Highlighting that the linker length of drug linkers is an important structural property for peak separation in HIC
