Company: Seoul National University College of Medicine
Job title: Department of Biochemistry and Molecular Biology
Dr. Junho Chung graduated from Seoul National University, College of Medicine and received his M.D. degree. After his graduation, he joined a dual degree program at the same college and obtained his Ph. D. degree as a molecular biology major under the supervision of Prof. Hong-Keun Chung.
Then he joined the late Dr. Carlos F. Barbas III’s laboratory at The Scripps Research Institute, La Jolla, CA, USA as a research associate, who is one of the pioneers in the field of recombinant antibody engineering.
From 2000, Dr. Chung has been a faculty of Seoul National University, College of Medicine at the Department of Biochemistry and Molecular Biology. He is also a founding member of National Cancer Center Korea, in which he served as a director of basic science division for four years as a dual duty.
His research has been focused on antibody engineering. He published more than 99 articles in this field and invented more than 30 registered patents. Until now, seventeen of his patents and know-hows were licensed to nine biotech companies. An anti-HGF antibody he invented successfully finished Phase I clinical trial (ClinicalTrials.gov Identifier: NCT02499224, Safety and Pharmacokinetics Study of YYB101 in Advanced Solid Tumors Patients Who Are Refractory to Standard Therapy). And Phase II trial started in July 2019. Two other antibodies are in preclinical development stage. Recently, he is also actively developing technologies applicable to the chimeric antigen receptor T cell therapy too.
Efficient Selection & Optimization of the Antibody for Antibody Drug Conjugates 4:30 pm
Selection of antibody for ADC using machine learning and next-generation sequencing High throughput screening of antibody for ADC using anti-target x hapten bispecific antibody and hapten-conjugated linker payload Optimization of antibody for stabilityRead more
day: Day Two