Multi-arm Linker Units with Drug Molecules or Chelator Groups for Preparing Antibody Drug or Radionuclide Conjugates

Time: 2:40 pm
day: Day One


  • Understanding how a drug bundle is prepared; By conjugating 3-5 cytotoxic drug molecules or chelator groups to a multi-arm linker
  • Two drug bundles are conjugated to the C-termini of H chains of an antibody molecule via a click reaction or SH-maleimide reaction
  • Reviewing one ADC with lenalidomide bundles and one ARC with DOTA chelator bundles