Multi-arm Linker Units with Drug Molecules or Chelator Groups for Preparing Antibody Drug or Radionuclide Conjugates
Time: 2:40 pm
day: Day One
Details:
- Understanding how a drug bundle is prepared; By conjugating 3-5 cytotoxic drug molecules or chelator groups to a multi-arm linker
- Two drug bundles are conjugated to the C-termini of H chains of an antibody molecule via a click reaction or SH-maleimide reaction
- Reviewing one ADC with lenalidomide bundles and one ARC with DOTA chelator bundles
Speakers:
Dr. Tse Wen Chang is the founder and CEO of Immunwork based in Taipei, Taiwan. He was the inventor of Xolair and a cofounder of Tanox, which went public in 2000, raising a record US$ 280M, and was acquired by Genentech in 2007. His new invention of T-E technology platform is suitable for developing a…Read more